Features of Diagnostics and Treatment of Drug-Resistant Forms of Pulmonary Tuberculosis

Abstract

The prevalence of MDR -tuberculosis has increased by 5.9 times over the past 14 years. A serious problem for the TB service, only in a quarter of the newly detected bacterial excretors, due to poor laboratory equipment, the presence of Mycobacterium tuberculosis in the diagnostic material was determined by the cultural method, which means that in 3/4 of the newly detected bacterial excretors there is no possibility of determining the drug sensitivity of the pathogen, and such patients are treated without determining sensitivity to anti-tuberculosis drugs. These data indicate that at present there are a number of obstacles to the effective fight against tuberculosis, where drug resistance (DR) of MBT to anti-tuberculosis drugs, as well as the state of the immunobiological forces of the body is the main ones.