Morphological Aspects of the Liver of White Outbred Rats After Severe Traumatic Brain Injury Caused Experimentally in the Form of a Road Accident

Abstract

The study was conducted on 60 white outbred rats 3 months of age. The fixed animals were accelerated on a vehicle made by hand in the form of a vehicle on wheels, and hit a wooden barrier with the frontal part of the head. As a result of this experiment, 16 white rats died on the spot. All dead rats during the experiment were instantly decapitated by decapitation. After opening the abdominal cavity, the liver was removed. The seized liver was examined and studied, and its dimensions were measured in the prescribed manner. The liver was fixed in Bouin's solution and embedded in paraffin according to generally accepted rules. Next, histological sections were prepared with a thickness of 6-7 μm, which were stained with hematoxylin-eosin. Morphometric studies of the liver tissue were performed under an NLCD-307B microscope. In 3-month-old rats, the total thickness of the liver wall in its various ranges remained unchanged, but some changes in the tissue structures of the liver were revealed.