The Relationships between Obesity and Increased Serum TSH Level in Euthroid Subjects
Keywords:Obesity, Serum TSH Level, Euthroid Subjects, body mass index BMI, T3, T4
Objectives: To investigate the relationship between circulating TSH level and adiposity in cohort of obese people who have normal, thyroid function.
Methods: Cross sectional analysis was carried out on 110 thyroid obese or overweight female subjects. Twenty male lean and thyroid subjects (BMI < 25Kg/m2), were included in the study group. Thyroid stimulation hormone (TSH) total thyroxin T4 total triiodothyronine T3, body weight, height, body mass index (BMI) was assessed.
Results: TSH level were higher the obese than in the lean subjects, in the study group (lean and obese subjects) there was increase serum TSH with increasing degree of BMI. There was no correlation between serum TSH and age. There was no correlation between serum T4 and body mass index (BMI).
Conclusion: This study strongly supports existing, but contradictory evidence that seruum TSH levels are positively correlated with the degree of obesity in overweight people with normal thyroid function.