Modern Aspects of Polycystic Ovary Syndrome (Review)

Abstract

Polycystic ovary syndrome (PCOS) is a fairly common disease, which is one of the most pressing problems in gynecological endocrinology. The review article provides current data on the etiology and pathogenesis of PCOS. The rationale for the frequent combination of hyperandrogenism and insulin resistance in PCOS is given. It also discusses the characteristic clinical manifestations of PCOS and modern approaches to diagnosis and treatment, including drugs with neurotransmitter action (sibutramine, orlistat), drugs from the group of insulin sensitizers - metformin, progestogens or low-dose single-phase COCs with 3rd generation progestogens, synthetic antiestrogen - clostilbegit, and other drugs. . The prospects and methods of surgical intervention and tactics for infertility against the background of PCOS are considered.