2-Isopropyl-5-Methylphenylchloroacetate Synthesis Method

Authors

  • Abdushukurov Anvar Kabirovich Professor of the Faculty of Chemistry of the National University of Uzbekistan
  • Mamatkulov Nematillo Narzullaevich Associate Professor of the Faculty of Chemistry of the National University of Uzbekistan
  • Ibragimov Takhirbek Egamshukurovich Teacher of the Faculty of Chemical Technology of Inorganic Substances, Tashkent Institute of Chemical Technology
  • Jadilova Dilnavoz Abdulazizovna Student of the Faculty of Chemistry of the University of Technical Uzbekistan

Keywords:

Chloroacetyl chloride, phenol, cresol, catalyst, benzene, solvent, extraction, vacuum, flask, sodium metal, O-acylation, S-acylation, inglet, mixture, 1,4- benzodioxane

Abstract

In this article, the reaction of 2-isopropyl-5-methylphenol with chloroacetyl chloride with benzene and 1,4-benzodioxane was carried out for the first time. It was found that the yield of the substance in this reaction depends on the solvent and the reaction conditions. It was observed that the reaction of  2-isopropyl-5-methylphenol with sodium metal leads to chloroacetylation of 2-isopropyl-5-methylphenolate. The structure of the new substance formed was confirmed by IR-, H1 СMR and C 13  СMR spectra.

 

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Published

2023-04-10

Issue

Vol. 2 No. 4 (2023): APRIL

Section

Articles